“The picture on the left is my senior homecoming after being on prednisone for several months. About a week into taking the prednisone, I developed a very hot and burning face and neck. What is Prednisone? A 43-year-old female asked: i just weaned down from prednisone and i'm off of the steroid. See how to counteract eight common prednisone side effects, including fluid retention, and learn how proper prednisone … Prednisone is a synthetic steroid hormone meant to work similarly to the naturally-occurring hormone cortisol. Is this from the steroids? Are you at risk? Difficulty breathing is a common symptom of an allergic reaction to prednisone. My face felt like it was on fire and my whole head was red. but now my face is extremely red and i'm very hot. Swelling of the face, lips, or tongue are common symptoms of an allergy. The phase IV clinical study is created by eHealthMe based on reports of 399,836 people who have side effects when taking Prednisone from the FDA, and is updated regularly. My face turns a little red-- I look a little flushed. Methylprednisolone may suppress the inflammatory response to skin tests. Is this something that happens with steroids? Dr. Gebrehana Zebro (formerly Woldegiorgis) answered. Support Forums > ... Posted 1/6/2010 7:40 PM (GMT -7) I just started the mega dose pack of prednisone and all day people looked at me like i was about to have a stroke. It can alter the menstrual cycle, causing periods to become irregular. Face turning red and burning after starting prednisone. prednisone red face. I had serious weight gain and ‘moon face!’ The picture on the right is the following summer after being off of prednisone and getting back to my normal, healthy weight.” — Brianna D. Red skin syndrome (RSS) is caused by long-term or excessive use of topical steroid drugs. I have been off the prednisone for 2 days but am still experiencing the symptoms. It seems to have swollen just a tad since this morning. You should refer to the prescribing information for methylprednisolone for a complete list of interactions. i never had any side effects. Skin blushing/flushing is found among people who take Prednisone, especially for people who are female, 60+ old, have been taking the drug for < 1 month. 31 years experience Internal Medicine. Find out more about the symptoms and causes. ... Methylprednisolone may induce problems with menstruation in women who take the medicine 1. Raised red areas of skin, commonly known as hives, may also develop. LBJ. 8 Prednisone Side Effects + How to Minimize Them. It also can cause a condition known as amenorrhea, which means periods suddenly stop without pregnancy occurring. Flushing causes the skin to become hot and the face will turn red. 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